DNA Detection and Signal Amplification via an Engineered Allosteric Enzyme
نویسندگان
چکیده
منابع مشابه
Signal amplification and detection via a supramolecular allosteric catalyst.
The design of a supramolecular allosteric catalyst system for catalytic signal amplification and detection is presented. The catalyst was switched "on" by the introduction of an analyte that also behaves as an allosteric activator. Concentrations of Cl- ions as low as 800 nM were catalytically amplified and detected. The signal was transduced via a pH-sensitive fluorescent probe and observed vi...
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ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 2003
ISSN: 0002-7863,1520-5126
DOI: 10.1021/ja027885u